ULTRASTRUCTURAL ANALYSIS OF SMALL BLOOD VESSELS IN SKIN BIOPSIES IN CADASIL


Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses

Hearing relies on rapid, temporally precise, and sustained neurotransmitter release at the ribbon synapses of sensory cells, the inner hair cells (IHCs).This process requires otoferlin, a six C2-domain, Ca2+-binding transmembrane peperomia double duty protein of synaptic vesicles.To decipher the role of otoferlin in the synaptic vesicle cycle, we p

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Micro-Doppler Frequency Extraction and Scatterer Classification for a Smooth-Surfaced Cone-Shaped Precession Target Under Narrowband Radar

The micro-Doppler (μD) characteristics of ballistic targets are crucial for estimating motion and structural parameters, as well as for target recognition.However, existing time-frequency (TF) analysis methods are predominantly nonparametric and suffer from limited resolution, making it challenging to accurately extract μD TF curves.T

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